Posted by u/User_741776
"Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system"
Howdy folks! So here's something that's being talked about in the hair loss (and those just passionate about hair, like me lol) community I wanted to bring more attention to. Researchers in Japan were able to (for the first time) grow fully functional hair follicles in a vitro culture system, which were able to begin the hair cycle process. Not only that, but later these hairs were attached to mice (again because mice apparently have the cure to everything now /j) tissue and actually began to attach themselves, connecting to nerves and forming arrector pili muscles. The main driving force behind all of this is stem cell technology. The process begins with the epithelial stem cells (they make the hair), and the dermal papilla cells (they tell the hair to grow), but only these two types of cells were identified for the longest time. This is why hairs that were initially cloned struggled to actually cycle and attach to tissue. Recently, in this study, a new type of cell was discovered to play a pivotal role in hair growth, the accessory mesenchymal cells. These cells provide scaffolding and structure, particularly around the follicle's 'bulge' and as part of a covering called the dermal sheath. Adding these cells seemed to do the trick, and thus, the hair began to actually do it's thing. This is really exciting news, not only for those with androgenic alopecia (the fancy name for male pattern baldness), but for other fields regarding hair as well. Hypothetically, in the future this process would allow someone to clone their body hairs and increase density where ever they choose (think thicker eyebrows, more beard hairs, etc.). This technology would also (hypothetically) be able to work with other animals. You'd be able to get authentic horse hair without ever having to pull a whole mane's worth. Overall, I'm just really stoked to hear about this and thought it was something y'all would like to now Also the link is directly to the paper the researchers released (not an article about the paper trying to make some extra bold sensational claim). It goes into insane detail about all this lol
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